Recently, molecular biological studies have revealed that PTPS are one of the most common regulators of signal transduction pathways that are involved in regulating these complex pathophysiologies. The deregulation of protein tyrosine phosphorylation is a key event in the pathogenesis of numerous neurodegenerative diseases, including Huntington's disease, Alzheimer's disease and amyotrophic lateral sclerosis (ALS). It brings some changes and improvements for Mac users.Towards a molecular basis of neurodegeneration: application of protein tyrosine phosphatases to signal transduction and degeneration.
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